THALIDOMIDE DECREASES GELATINASE PRODUCTION BY MALIGNANT B LYMPHOID CELL LINES THROUGH DISRUPTION OF MULTIPLE INTEGRIN-MEDIATED SIGNALING PATHWAYS

Thalidomide decreases gelatinase production by malignant B lymphoid cell lines through disruption of multiple integrin-mediated signaling pathways

Background Thalidomide and its analogs are effective agents in the treatment of multiple myeloma.Since gelatinases (matrix metalloproteinases-2 and -9) play a crucial role in tumor progression, we explored the effect of thalidomide on gelatinase production by malignant B lymphoid cell lines.Design and Methods We investigated the effect of therapeut

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Research Project for the Relocation of Informal Traders From the Oriental Market in the City of Riobamba, Year 2022

The increase in informal activities is a problem in the Ecuadorian economy and those who develop it are considered vulnerable groups since they do not have a permanent job with due benefits of the law that a formal job would offer them.Since their economic income Pulling Breast Collars is unstable, they run the risk of financial vulnerability.The p

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